San Diego County COVID-19 Update – 4-22-2021

coronavirus illustration
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Here is today’s COVID-19 update from the County Health and Human Services Agency with data through April 21.

Vaccination Progress:

  • Over 2.62 million COVID-19 vaccine doses have been delivered to the region, and close to 2.41 million have been logged as administered. This number includes both County residents and those who work in San Diego County.
  • Overall, more than 1.33 million County residents have received at least one shot of the two-dose vaccine. That’s 49.5% of those eligible.
  • Of those vaccinated to date, over 863,000 County residents, or 32.1% of San Diegans 16 and older, are fully immunized.
  • The goal is to fully vaccinate 75% of San Diego County residents 16 and older or 2,017,011 people. To date, 66.0% of the goal population has received at least one vaccine and 42.8% are fully vaccinated.
  • Those who received the one-dose Johnson & Johnson vaccine, which is currently on hold in the County due to guidance from the Centers for Disease Control and Prevention and Food and Drug Administration, are being added to the total of fully vaccinated San Diegans.
  • The difference between doses shipped and the number of vaccinations administered represents approximately what is expected to be used in the next seven days and doses still to be entered in the record system.
  • More information about vaccine distribution can be found on the County’s vaccination dashboard. For vaccination opportunities, visit

State Metrics:

  • San Diego County’s state-calculated, adjusted case rate is currently 6.1 cases per 100,000 residents (as of April 20).
  • The County remains in the Orange Tier or Tier 3 under the state’s new guidance. The California Department of Public Health indicates that unless there are extenuating circumstances, such as low rate of vaccine uptake, a county will only move to a more restrictive tier if hospitalizations are increasing significantly among vulnerable individuals, especially among vaccinated individuals, and both testing positivity and adjusted case rates show a concerning increase in transmission. This is currently not the case in the region.
  • Currently, the testing positivity percentage is 2.4%, placing the County in Tier 3 or the Orange Tier.
  • The County’s health equity metric, which looks at the testing positivity for areas with the lowest healthy conditions, is 3.0% and is also in the Orange Tier or Tier 3.
  • CDPH assesses counties on a weekly basis. The next report is scheduled for Tuesday, April 27.

Community Setting Outbreaks:

  • Five new community outbreaks were confirmed April 21: two in restaurant/bar settings, one in a business setting, one in a daycare/preschool/childcare setting and one in a retail setting.
  • In the past seven days (April 15 through April 21), 23 community outbreaks were confirmed.
  • The number of community outbreaks remains above the trigger of seven or more in seven days.
  • A community setting outbreak is defined as three or more COVID-19 cases in a setting and in people of different households over the past 14 days.


  • 17,425 tests were reported to the County on April 21, and the percentage of new positive cases was 2%.
  • The 14-day rolling average percentage of positive cases is 1.7%. Target is less than 8.0%.
  • The 7-day, daily average of tests is 12,798.

Cases, Hospitalizations and ICU Admissions:

  • 281 COVID-19 cases were reported to the County on April 21. The region’s total is now 275,912.
  • 15,214 or 5.5% of all cases have required hospitalization.
  • 1,678 or 0.6% of all cases and 11% of hospitalized cases had to be admitted to an intensive care unit.


  • Three new COVID-19 deaths were reported April 21. The region’s total is 3,684.
  • Two women and one man died between April 18 and April 20.
  • Of the people who died, one was 80 years of age or older and two were in their 60s.
  • Two had underlying medical conditions and one did not.

More Information:

The more detailed data summaries found on the County’s website are updated around 5 p.m. daily.


Katie Cadiao is a communications specialist with the County of San Diego Communications Office. Contact